Thermo Scientific Acclaim Trinity Q1 HPLC column for LC-MS herbicide analysis

The Thermo Scientific Acclaim Trinity Q1 HPLC column is designed to facilitate high-resolution and high-throughput trace analysis of the herbicides diquat and paraquat in plants by liquid chromatography-mass spectrometry (LC-MS).

Diquat and paraquat are non-selective herbicides that are widely used in agriculture and by government agencies and industries for control of weeds. Both are considered to be toxic, and paraquat has been linked to Parkinson’s disease among farm workers. While the dangers of the pesticides, when concentrated, are well documented, the effects of residual levels of these pesticides in food require additional research.

Acclaim Trinity Q1 columns are reported to deliver the retention, resolution, peak shape and speed needed to improve diquat and paraquat LC-MS analysis in common terrestrial and aquatic plant matrices. The stable baseline separation for diquat and paraquat reduces the challenges of achieving accurate detection and quantitation compared to reversed-phase column methods.

The column contains Nanopolymer Silica Hybrid (NSH) technology that, unlike other support systems, does not require ion pair reagents or exotic mobile phases to separate diquat and paraquat for LC-MS analysis. The cation-exchange function provides retention and separation for diquat and paraquat while the anion-exchange moiety effectively deactivates the undesirable interaction between the surface silanols and the analytes.